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Tumor Antigen Specific Activation of Primary Human T-Cells Expressing a Virally Encoded Chimeric T-C
We have developed and tested chimeric T-cell receptors (TCR) specific for p185HER2. In these experiments, retroviral vec......
AIM: To investigate the pathological effect of Helicobacter pylori (H pylori) on human hepatic cells, proteomic methods ......
Up-regulation of NKG2D ligand ULBP2 by matrine in K562 cells and the underlying molecular mechanisms
Objective To probe matrine acting on natural killer cell(NK)activating receptor NKG2D ligands expression in CML cell lin......
Various mutants defective in phytohormone biosynthesis and signaling pathways have been identified and characterized rec......
Down-regulation of STAT3 expression by vector-based small interfering RNA inhibits pancreatic cancer
AIM:To evaluate the effect of RNA interference (RNAi) mediated silence of signal transduction and activation of transcri......
MicroRNAs (miRNAs) are a class of non-coding RNAs that play critical roles in post-transcriptional regulation. Their tar......
Nitrate and ammonium are two major nitrogen(N) sources for higher plants,but they differ in utilization and signaling.Mi......
利用含胶质源性神经营养因子(Glial cell derived neurotrophic factor,GDNF)基因的慢病毒载体转染了人胚胎来源的神经干细胞,探讨了......