cabazitaxel相关论文
Until recently,docetaxel-based therapy represented the only therapy shown to prolong survival in patients with metastati......
The development and progression of metastatic castration-resistant prostate cancer is the major challenge in the treatme......
prostate cancer has been recognized as being responsive to androgen deprivation since the 1940s when Charles Huggins ifr......
Taxanes have been used extensively for various types of cancer for nearly two decades[1].Cabazitaxel (Cbz),with antitumo......
Although the antitumor drug cabazitaxel shows great therapeutic potential,its high toxicity and poor water solubility li......
赛诺菲-安万特公司开发的新型紫杉烷类化疗药物Jevtana(cabazitaxel)在一项名为TROPIC的Ⅲ期临床研究中获得成功,该研究结果显示,J......
Cabazitaxel是一种用于治疗晚期前列腺癌的新药,由赛诺菲-安万特公司研制,2010年6月获美国FDA批准上市。该药是紫杉烷类化合物[1],......
Cabazitaxel是一种用于治疗晚期前列腺癌的新药,由赛诺菲-安万特公司研制,2010年6月获美国FDA批准上市。该药是紫杉烷类化合物[1],......
Cabazitaxel(商品名JEVTANA)是一种新型紫杉烷类化疗药物。由紫杉类植物的提取物合成。其化学名为(2α,5β,7β,10β,13α)-4-乙酰......
A facile and universal method to achieve liposomal remote loading of non-ionizable drugs with outsta
Liposomes have made remarkable achievements as drug delivery vehicles in the clinic.Lipo-somal products mostly benefited......
本文报道了一种以10-去乙酰基巴卡丁Ⅲ为起始原料合成卡巴他赛的新方法.路线中使用了温和的条件对底物7-羟基进行甲醚化,从而避免......
目的建立并应用超高效液相色谱-串联质谱法(UPLC-MS/MS)测定人血浆中卡巴他赛与血浆蛋白的结合率。方法以拉洛他赛为内标,样品经叔......
Cancer metastasis is the primary cause of high mortality in breast cancer patients.In this study,we loaded an anti-cance......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
直到最近，基于 docetaxel 的治疗代表了显示出与变形阉割抵抗的前列腺癌症(mCRPC ) 在病人延长幸存的唯一的治疗。过去的年和一半被......
六不同治疗在与变形阉割抵抗的前列腺癌症(mCRPC ) 指向到病人的阶段 III 试用表明了改进幸存。为 mCRPC 的前线的治疗学的选择包......
当查尔斯·哈金斯首先在管理这些病人描述了外科的阉割的角色时，先进前列腺癌症作为自从 1940 年代，对雄激素剥夺应答被认出了。......
赛诺菲一安万特公司开发的新型紫杉烷类化疗药物Jevtana（cabazitaxel）在一项名为TROPIC的Ⅲ期临床研究中获得成功，该研究结果显示，Jevt......
Future Directions in Metastatic Castration Resistant Prostate Cancer (mCRPC): Clinical Rationale and
Several recent studies in mCRPC have identified the mechanisms of tumoral growth after the disease becomes unresponsive ......
本文介绍了卡巴他赛原料药的一种手性异构体杂质（2α,5β,7β,10β,13α）-4-乙酰氧基-2-苯甲酰氧基-5,20-环氧基-1-羟基-7,10-二甲氧......
一项对赛诺菲一安万特公司的新分子实体cabazitaxel（商品名：Jevtana）进行的名为TROPIC的Ⅲ期临床试验结果于2010年10月发表在《柳叶刀......
期刊
Prostate cancer is the most common non-cutaneous malignancy for men.The skeleton is the most common metastatic site but,......
A cabazitaxel liposome for increased solubility,enhanced antitumor effect and reduced systemic toxic
The potential side effects of cabazitaxel(CBZ)in the field of cancer treatment have become a great limitation to its fur......
<正>在美国,2009年因前列腺癌死亡的病例在27000人以上。雄激素去势治疗虽对大多数转移性前列腺癌患者均有效,但很容易产生抵抗。......
期刊
