Although single-particle cryogenic electron microscopy(cryo-EM)has been applied extensively for elu-cidating many crucia......

Although single-particle cryogenic electron microscopy(cryo-EM)has been applied extensively for elucidating many crucial......

　　Macroautophagy is a catabolic pathway that targets large, long-lived structures such as protein aggregates, damaged ......

The CryoEM single particle structure determination method has recently received broad attention in the field of struc-tu......

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Capsaicin in chili peppers bestows the sensation of spiciness.Since the discovery of its receptor,transient receptor pot......

Mechanosensitive (MS) channels are extensively studied membrane protein for maintaining intracellular homeostasis throug......

Assembly of eukaryotic ribosome is a complicated and dynamic process that involves a series of intermediates.It is unkno......

Inhibition of Mycobacterium tuberculosis (Mtb) cell wall assembly is an established strategy for anti-TB chemotherapy.Ar......

Intracellular compartmentation is a key strategy for the functioning of a cell.In 2010,several studies revealed that the......

冷冻电子显微学作为结构生物学主要工具之一,以解析承担生命活动中重要功能的各种蛋白质机器三维结构为手段,对其在生命活动中的功......