dopaminergic相关论文
Animals respond differently to visual cues with distinct ethological meaning,a process usually thought to be achieved th......
Animals respond differently to visual cues with distinct ethological meaning,a process usually thought to be achieved th......
OBJECTIVE Dysfunction of the dopaminergic(DA)neurons is implicated in the pathogenesis of bipolar disorder(BPD).Hista⁃m......
Dopaminergic neurotoxicity is characterized by damage and death of dopaminergic neurons.Parkinson\s disease(PD)is a neu......
Stress increases MHC-I expression in dopaminergic neurons and induces autoimmune activation in Parki
The expression of major histocompatibility complex class I(MHC-I),a key antigen-presenting protein,can be induced in dop......
目的:研究司来吉兰(selegiline,Sel)的神经保护作用及其对单胺氧化酶B(MAOB)的抑制作用.方法:高效液相电化学检测法测定小鼠纹状体内多巴胺(DA)及其代谢产物的......
目的 探讨甲基磺酸敏感蛋白2(MMS2)在血管紧张素Ⅱ(AⅡ)诱导神经干细胞(NSCs)向多巴胺(DA)能神经元定向分化过程中的作用.方法 体......
帕金森病(PD)是一种中老年人常见的神经退行性疾病,其致病因素尚不明确。遗传、饮食习惯、环境毒素、免疫学异常、炎症、氧化应激......
目的:探索胶质源性神经营养因子(GDND在体外诱导小鼠胚胎中脑神经干细胞(M—NSCs)分化成多巴胺能神经元的培养方法,为M—NSCs移植治疗帕......
In the last few decades,intracerebral transplantation has grown from a dubious neuroscientific topic to a plausible moda......
帕金森病是中脑黑质的多巴胺能神经元缺失引起的慢性中枢神经系统功能失调。目前,应用神经干细胞在体内外分化成多巴胺能神经元是......
目的检测Sonic Hedgehog蛋白(Shh)在帕金森病(Parkinson’s disease,PD)大鼠中脑黑质的表达。方法将健康SD大鼠(雌雄不拘)随机分成3组:正常......
Parkinson’s disease is the second most common neurodegenerative disorder;it affects 1%of the population over the age of......
本文采用细胞外记录方法探讨缰核与黑质在痛觉机制中的关系。结果表明单脉冲刺激外侧缰核(LHb),可抑制大多数黑质致密部(SNC)多巴......
且的应用GDNF和GM1体外联合诱导MSCs转化为多巴胺能(DA)神经元。探索体外诱导MSCs定向分化为DA能神经元的最佳条件。方法取雄性Wista......
目的探讨青年和老年大鼠黑质DA能(DA)神经元对脂多糖(LPS)所诱导的损伤作用的敏感性差异和对小胶质细胞活性的影响。方法采用立体定向......
Subcutaneous Rotenone Injection Destroys Dopaminergic Neurons and Induces Parkinsonism Symptoms in R
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Parkinson’s disease(PD)is an age-related neurodegenerative disease caused by the progressive loss of dopaminergic(DA)ne......
目的探询"双固一通"针法对帕金森病模型大鼠黑质多巴胺能神经元的保护作用.方法将Wistar大鼠40只,随机分为正常对照组、假手术对照......
Levodopa uptake from the gastrointestinal tract in patients with Parkinson’s disease (PD) can be affected by delayed ga......
Long-term adenosine A1 receptor activation-induced sortilin expression promotesα-synuclein upregulat
Prolonged activation of adenosine A1 receptor likely leads to damage of dopaminergic neurons and subsequent development ......
We previously reported that intranasal insulin protects substantia nigra dopaminergic neurons against 6-hydroxydopamine ......
Human adult olfactory epithelium contains neural progenitors (hONPs) which replace damaged cellular components throughou......
目的探讨骨髓基质干细胞对帕金森病的疗效.方法用6-OHDA破坏SD大鼠一侧黑质,建立帕金森病模型,采用立体定向仪,将BrdU标记的骨髓基......
A mutation in protein kinase C-gamma alters SNC neuron morphology and decreases synaptic vesicles in
A spontaneous mutation in the Albino Swiss (AS) rat has been shown to be a single point mutation (agu) in the gene codin......
Anhedonia can be defined as a condition in which the hedonic capacity is totally or partially lost. From a psychobiologi......
Parkinson’s disease (PD) or Paralysis Agitans was first formally described in “An essay on the shaking palsy”, publis......
Pain in Parkinson’s disease is common, with an estimated prevalence up to 85% of those with the disease. Central pain i......
Comparison of continuous versus pulsatile dopaminergic therapy in the erderly with Parkinson’s Disea
Objective: Levodopa is the gold-standard of therapy in Parkinson’s disease (PD), but it is associated with motor compli......
Dopaminergic therapy can improve motor functioning in Parkinson’s disease (PD), but its effect on spoken discourse is p......
Dopaminergic therapy can improve motor functioning in Parkinson’s disease (PD), but its effect on spoken discourse is p......
OBJECTIVE To research the effect of naringenin (NAR) on LPS-induced dopaminergic neurons damage and its potential mechan......
Dopamine and its receptors have been widely studied in the neurological conditions and in the retina. In this study, we ......
Astrocytes and astrocyte-related proteins play important roles in maintaining normal brain function,and also regulate pa......
For decades,clinicians have developed medications and therapies to alleviate the symptoms of Parkinson’s disease,but no......
Objective:Monoamine system plays a key role in the pathophysiology of a wide range of neuropsychiatric disorders includi......
Objective: To determine if there is a significant rise in serum prolactin (PRL) in acute psychosis related to disease pr......
Thirst, which provides the motivation to drink, is an important component of the coordinated sequence of physiological r......
The Effects of Zinc and Other Divalent Cations on M-Current in Ventral Tegmental Area Dopamine Neuro
Ventral tegmental area dopamine (DA VTA) neurons are important for the reinforcing effects of drugs of abuse such as eth......
Glial cell line-derived neurotrophic factor(GDNF) plays a critical role in neuronal survival and function. GDNF has two ......