pyrazolo[3相关论文
Design,synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FG
Fibroblast growth factor receptors(FGFRs)have emerged as promising targets for anticancer therapy.In this study,we synth......
Synthesis, Crystal Structure, and Antitumor Activity of 1-(4-Methoxybenzylidene)-2-(1-phenyl-6-trifl
本文通过对荣华二采区10...
An unexpected reaction of cyanothioacetamide: Novel preparation of pyrazolo[3,4-b]-pyridine derivati
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
A novel synthesis of pyrazolo[3,4-b]pyridine derivatives through multi-component reaction in ionic l
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Microwave-assisted synthesis of some novel fluorinated pyrazolo[3,4-d]pyrimidine derivatives contain
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
A one-pot,three-component condensation reaction of an aldehyde,benzoyl acetonitrile(3-oxo-3-phenylpropane nitrile) and 6......
An efficient regioselective sonochemical synthesis of novel 4-aryl-3-methyl-4,5-dihydro-1H-pyrazolo[
An efficient ultrasound-assisted preparation of a series of novel 4-aryl-3-methyl-4,5-dihydro-l//-pyrazolo[34-b]pyridin-......
标题化合物（C24H16N4S）以噻吩-2-甲醛、苯甲酰乙腈和3-甲基-1-苯基-1H-吡唑-5-胺为原料,在离子液体[bmim]Br溶剂中,在80℃搅拌合成得......
An unexpected reaction of cyanothioacetamide: Novel preparation of pyrazolo[3,4-b]-pyridine derivati
An unexpected multi-component reaction of cyanothioacetamide with aldehyde and aminopyrazole under MWI was reported. Thr......
Microwave-assisted synthesis of some novel fluorinated pyrazolo[3,4-d]pyrimidine derivatives contain
A facile microwave-assisted procedure for synthesis of novel fluorinated pyrazolo[3,4-d]pyrimidine derivatives containin......
An efficient regioselective sonochemical synthesis of novel 4-aryl-3-methyl-4,5-dihydro-1H-pyrazolo[
An efficient ultrasound-assisted preparation of a series of novel 4-aryl-3-methyl-4,5-dihydro-1H-pyrazolo[3,4-b]pyridin-......
吡唑并[3,4-b]吡啶可用作HSP90抑制剂、FGFR激酶抑制剂、mGluR5正变构调节剂等.现有的合成方法存在容易爆炸、产率不高、时间过长......
以色酮类化合物和1,3-二取代5-氨基吡唑化合物为原料,在分子碘催化下制备一系列新颖的多取代吡唑[3,4-b]吡啶衍生物(3a～3j),收率高......
用荧光光谱法和紫外-可见吸收光谱法研究了在模拟人体生理条件下吡唑[3,4-b]并吡啶类药物和人血清白蛋白（HSA）结合反应的特征,并利用......
膦亚胺与芳基异氰酸酯、取代酚的连续aza-Wittig反应和关环反应合成了新的2-[4-(1-苯基-3-苄硫(砜)基-5-取代芳基-4(5H)-酮-1H-吡......
以5-氨基-1-芳基-1H-吡唑-4-甲腈为原料,在氢氧化锂催化下与邻氯硝基苯反应制得1-取代苯基-4-氰基-5-（2-硝基苯氨基）-1H-吡唑,然后经......
标题化合物（C30H35N3）以4-甲基苯甲醛、环十二酮和3-甲基-1-苯基-1 H-吡唑-5-胺,在三氟乙酸和醋酸的作用下,经微波辐射合成得到.其结......
合成了14种1－苯基－3－氨基－5－氧代－4－取代腙吡唑及其关环产物吡唑[3,4-e]并－1，2，4－三嗪和吡唑[3,4-e]并－1，2，3，4－四嗪衍生物，经元素分析，IR^1H NMR和MS......
The novel title compound 1-(4-methoxybenzylidene)-2-(1-phenyl-6-trifluoromethyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)hydrazi......
A new series of 3-(methylthio)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine derivatives was synthesized. The structures of the ......
A Novel One-Pot and Efficient Procedure for Synthesis of New Fused Uracil Derivatives for DNA Bindin
Hydrazinolysis of 6-chloro-1-methyluracil followed by condensation of the product with different aromatic aldehyde gives......
Azoniaallene salts as versatile building blocks in the synthesis of antibacterial and antifungal het
Substituted 2-azoniaallene salts 1 are strong bifunctional electrophiles, undergo cyclization reactions furnish many ser......
An unexpected reaction of cyanothioacetamide： Novel preparation of pyrazolo[3,4-b]-pyridine derivati
有在 MWI 下面的醛和 aminopyrazole 的 cyanothioacetamide 的意外多部件反应被报导。通过这反应，一系列 pyrazolo [3,4-b ]-pyrid......
A novel synthesis of pyrazolo[3,4-b]pyridine derivatives through multi-component reaction in ionic l
为 pyrazolo 的准备的一个有效、新奇的过程[3,4-b ] 通过醛， 5-amino-3-methyl-1-phenylpyrazole 和 malononitrile 或 cyanoaceta......
Synthesis of Novel Heteropolycyclic Nitrogen Systems Bearing Fluorine Substituted Pyrazolo[3,4-d] Py
Novel heteropolycyclic nitrogen systems bearing fluorine substituted pyrazolo[3,4-d] pyrimidine moiety have been synthes......
Condensation of D-glucose, o-phenylenediamine and N,N-benzylphenylhydrazine hydrochloride (NNBPHH) in a one-pot reaction......
The synthesis, preparation, chemical reactivities and biological activity of simple heterocyclic and heteropolycyclic ni......
4种1-苯基-3-氨基-5-氧代-4-苯偶氮吡唑衍生物1的合成,并对1进行重氮化、关环形成相应的2H-2-苯基-3-氧代-5H-5-取代苯基吡唑并[3,......
