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Objective Perfusion imaging using CT can provide additional information about tumour vascularity and angiogenesis in different glioma grades.The purpose of our study was to investigate the morphologic characteristics of supratentorial gliomas at different tumoural regions using PCT parameters and to quantitative estimate these imaging parameters for the assessment of the usefulness of PCT in glioma grading.Methods PCT was performed in 40 patients with previously untreated glioma (15 low-grade gliomas and 25 high-grade gliomas) by using a total acquisition time of 210 seconds on a 256-slice CT scanner.