The family of cyclic nucleotide-regulated ion channels includes the cyclic nucleotide-gated (CNG) channels, the hyperpolarization-activated cyclic nucleotide-mo
Transfer of ions across biological membranes is central to physiological processes like nerve excitation, muscle cell contraction, and hormone secretion.Ion cha
Ion channels selective for potassium (K+ channels) are involved in fine-tuning a plethora of physiological functions, such as the action potential duration and
Large-conductance calcium-activated potassium (BK) channels regulate the electric properties and neurotransmitter release in excitable cells.Its auxiliary (β)2
Hv1/VSOP is the minimalist ion channel where voltage sensor domain plays both roles in voltage sensing and proton permeation.Protomer of Hv1/VSOP can operate as
Voltage-gated calcium channels (VGCCs) are crucial for numerous physiological processes.Their activity is tightly regulated by diverse signaling molecules and p
Highly selective K+ channels play a key role in regulation of cellular excitability and electrolyte homeostasis.It was previously thought that ion selectivity o