Molecular insights into the membrane-associated phosphatidylinositol 4-kinase IIα

来源 :上海浦东免疫化学国际生物论坛 | 被引量 : 0次 | 上传用户:tzjgy
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Phosphatidylinositol 4-kinase IIα (PI4KIIα), a membrane-associated PI kinase, plays a central role in cell signaling and trafficking.Its kinase activity critically depends on palmitoylation of its cysteine-rich motif (-CCPCC-) and is modulated by the membrane environment.
其他文献
  NAC transcription factors are plant-specific and play important roles in plant development processes, response to biotic and abiotic cues and hormone signal
Cell calcium is controlled by binding to specific proteins.They belong to two different categories: proteins that bind calcium to process its signal, and are th
会议
The interactions of membrane proteins with their lipid bilayer environment play a key role in many aspects of their function.However, most structures are determ
会议
  14-3-3S are a class of conserved regulatory proteins ubiquitously existing in eukaryotes, which play important roles in a variety of cellular processes incl
IP3 receptor/PKC system is essential signaling systeminside the cell among which IP3 receptor (IP3R) system is directly linked to the Ca2+ signaling.Since IP3R
会议
Isoform 3 of the plasma membrane calcium ATPase (PMCA3 pump), which is highly expressed in brain and cerebellum, plays an important role in the regulation of ne
会议
The structure of theplasma membrane Ca2+ATPases (PMCA pumps) consists of 10 transmembranedomains, two large cytosolicloops, one of whichcontains the catalytic c
会议
The plasma membrane calcium +ATPase (PMCApump) is a calcium transporting protein in the plasma membrane of cells.Its role is the regulation of the homeostasis o
会议
Piwi-protein and piRNA pathway is mainly in the germline of a variety of species and exerts diverse functions including epigenetic regulation, transposon silenc
会议
Short-lived conformational states in proteins are fundamental to protein function, but tend to be difficult to detect due to their transient nature such as intr
会议