Mechanism and change of repolarization reserve in Rabbit with heart failure

来源 :The 4th International Ion Channel Conference(第四届国际离子通道会议) | 被引量 : 0次 | 上传用户：a7753834

【摘要】

：

【作者】

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Dexian Zhang Meiyan Chen Fang Zhou Tong Yin Jie Yang Qinglei Zhu Xi Chen Chao Zhu Yang Li

【机构】

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Institute of Geriatric Cardiology, the General Hospital of PLA, Beijing, China

【出处】

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The 4th International Ion Channel Conference(第四届国际离子通道会议)

【发表日期】

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2013年2期

【关键词】

：

heart failure repolarization reserve IKr IKs

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Aim: To research the mechanism of repolarization reserve change in rabbit heart failure model.Methods: 24 rabbits were divided randomly into Sham group and heart failure (HF) group.The ventricular myocytes were isolated by enzymatic method.Total cellular RNA was extracted, RT-qPCR was performed to compare the differences of KCNH2 and KCNQ1 between HF and Sham group in the level of mRNA.

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Mechanism and change of repolarization reserve in Rabbit with heart failure

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