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Background Calcification is a common finding in coronary arteries and has long been known to occur as a part of the atherosclerotic process.The purpose of this study was to observe the frequency and distribution of target lesion calcification in symptomatic coronary artery disease.Methods A total of 173 patients with Stable Angina (SAP) or acute coronary syndromes (ACS) were observed for the calcification in the native target lesion.Both angiography and intravascular ultrasound (IVUS) was performed to evaluate the frequency,amount and distribution of the target lesion.