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5. An α1-adrenoceptor antagonist: DDPH can efficiently attenuated the decreased expression of HCN1 mRNA

An α1-adrenoceptor antagonist: DDPH can efficiently attenuated the decreased expression of HCN1 mRNA

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：ameiameiiou

【摘 要】

：

Aim: DDPH (1-(2,6-dimethylphenoxy)-2-(3, 4-dimethoxyphenylethylamino) propane hydrochloride), a candidate drug known to be an a1-adrenoceptor antagonist,can efficiently penetrate through blood brain b

【作 者】

：

Jia-hong TAN Lian-jun GUO Zhi HE 

【机 构】

：

Department of Pharmacology, Tongji Medical College, Huazhong University of Science and Technology, W

【出 处】

：

The 12th Meeting of the Asia Pacific Federation of Pharmacol

【发表日期】

：

2013年4期

【关键词】

：

DDPH HCN1 mRNA rt-PCR chronic ischemia 

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Aim: DDPH (1-(2,6-dimethylphenoxy)-2-(3, 4-dimethoxyphenylethylamino) propane hydrochloride), a candidate drug known to be an a1-adrenoceptor antagonist,can efficiently penetrate through blood brain barrier and inhibit the contraction of vascular smooth muscle in the brain.

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