【摘 要】
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Backgrounds: TSP-1 is a glycoprotein that functions in the biology of bladder cancer.We investigated the relationship between the distribution ofTSP-1-1223 A/G polymorphism (rs2169830) and the clinica
【机 构】
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Department of Urology,The First Affiliated Hospital of Nanjing Medical University,210029
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Backgrounds: TSP-1 is a glycoprotein that functions in the biology of bladder cancer.We investigated the relationship between the distribution ofTSP-1-1223 A/G polymorphism (rs2169830) and the clinical characteristics of hladder cancer.Materials and methods: TaqMan assay was performed to determine the genotype of 609 cases and 670 control subjects in a Chinese population.Logistic regression was used to assess the association between the polymorphism and the risk of bladder cancer.Quantitative real-time polymerase chain reaction was performed to determine TSP-1 mRNA expression.Survival curves were generated using the Kaplan-Meier method.
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