【摘 要】
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Objective and methods: In this study, it was investigated for the effects of human selenoprotein SelK on the adhesion and migration ability of human gastric
【机 构】
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辽宁大学生命科学院,沈阳,110036
【出 处】
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2015医学前沿论坛暨第十四届全国肿瘤药理与化疗学术会议
论文部分内容阅读
Objective and methods: In this study, it was investigated for the effects of human selenoprotein SelK on the adhesion and migration ability of human gastric cancer BGC-823 cells using matrigel adhesion and transwell migration assays, respectively.Results: The matrigel adhesion ability of BGC-823 cells that overexpressed SelK declined extremely significantly (P<0.01), compared with that of the cells not expressing the protein.The migration ability of BGC-823 cells that overexpressed SelK also declined extremely significantly (P<0.01).On the other hand, the matrigel adhesion ability and the migration ability of the cells that overexpressed C-terminally truncated SelK not declined significantly.
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