血液循环肿瘤细胞在肺癌治疗中的临床价值研究

来源 :第十七届全国临床肿瘤学大会暨2014年CSCO学术年会 | 被引量 : 0次 | 上传用户:liouyun
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目的:近年来血液循环肿瘤细胞(Circulating tumor cell,CTC)检测已成为监测肿瘤病情、评价肿瘤治疗疗效的新方法.本研究旨在通过免疫磁珠负向富集技术结合靶向PCR技术(LT-PCR)的方法,检测肺癌患者外周血中CTC的灵敏度及特异性;比较CTC与血清肿瘤标志物检测肺部良恶性疾病的灵敏度及特异性;初步评价在晚期非小细胞肺癌(non-small cell lung cancer,NSCLC)予含铂双药一线化疗中CTC数量变化与临床疗效评价(RECIST 1.1)的相关性.
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