Alzheimers disease (AD), a progressively neurodegenerative disorder termed as irreversible cognitive and physical deterioration, is considered as one of the most common forms of dementia.The etiology of AD remains unknown, and no accurate treatment is available for reversing or alleviating this disease under the current conditions.Amyloid-β cascade theory suggests that the key event in the pathogenesis of AD is the abnormal production, aggregation and deposition of amyloid-β (Aβ) peptide, leading to the formation of senile plaques (SPs).