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Background: It is well known that the aberrant expression of programmed death ligand 1(PD-L1)on tumor cells impairs antitumor immunity.To date,in hepatocellular carcinoma(HCC),the relationship between PD-L1 expression and host-tumor immunity is not well defined.Methods: The expression levels of PD-L1 and CD8(+)T cell infiltration were analyzed by immunohistochemistry(IHC)in formalin fixed paraffin embedded(FFPE)specimens from 167 HCC patients undergoing resection.