【摘 要】
：
AIM:Eicosanoids are bioactive lipids metabolized from polyunsaturated fatty acids (PUFA).Common omega-6 and omega-3 PUFA such as arachidonic acid (ARA), lin
【机 构】
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TianjinResearchCenterofBasicMedicalScience,TianjinMedicalUniversity,Tianjin,China;DepartmentofPhysio
【出 处】
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2014 International Symposium on Polyunsaturated Fatty Acids
论文部分内容阅读
AIM:Eicosanoids are bioactive lipids metabolized from polyunsaturated fatty acids (PUFA).Common omega-6 and omega-3 PUFA such as arachidonic acid (ARA), linoleic acid (LA),eicosapentaenoic acid (EPA), docosahexaenoic (DHA) can be metabolized to hundreds of eicosanoids by cyclooxygenases (COX), lipoxygenases (LOX), cytochrome P450s (CYP450) enzymes and non-enzymatic auto-oxidation pathways.These eicosanoids take part in important biological processes such as reproduction, development, maintenance of body temperature and blood pressure, and play an important role in the development of many diseases, such as atherosclerosis, cardiomyopathies, hypertension, cancer and diabetes.
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