Catalyst-free sulfonylation of activated alkenes for highly efficient synthesis of mono-substituted

来源 :中国化学会全国第十一届有机合成化学学术研讨会 | 被引量 : 0次 | 上传用户:zhangqin0629
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Sulfones display a diverse range of behavior and possess unique feature that make them valuable to be starting materials for numerous types of synthetic applications.Recently, we focused our research in the catalyst-free sulfonylation reaction of activated alkenes with sulfonyl hydrazides under mild and environmentally benign conditions in water without any ligand or additive.The reaction gave a range of structurally diverse mono-substituted ethyl sulfones with excellent yields, in which the by-product was nitrogen.
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