【摘 要】
：
Electrospinning is a simple and robust method to produce micro and nanometer diameter fibers to mimic the architecture of extracellular matrix (ECM) for tis
【机 构】
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State Key Laboratory for Modification of Chemical Fibers and Polymer Materials,College of Materials
【出 处】
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The Third Symposium on Innovative Polymers for Controlled De
论文部分内容阅读
Electrospinning is a simple and robust method to produce micro and nanometer diameter fibers to mimic the architecture of extracellular matrix (ECM) for tissue engineering.However,the relatively small pores of electrospun scaffolds have become a bottleneck that limits efficient cellular infiltration and tissue ingrowth [1-2].To overcome this problem,we improved the electrospinning technique to make macroporous fibrous scaffolds.First,the composite fibrous scaffolds were formed by dualelectrospinning of PCL with PEO/NaCl salt (25-50 μm) onto a common rotating mandrel,and PCL macroporous scaffolds (pore size around 30 in) were created after PEO/NaCl salt dissolved in water,without difficulty in washing away salt embedded deep in the scaffolds.
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