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  5. Mixed Lineage Leukemia 5 (MLL5) Protein Regulates Cell Cycle Progression and E2F1-responsive Gene Ex

Mixed Lineage Leukemia 5 (MLL5) Protein Regulates Cell Cycle Progression and E2F1-responsive Gene Ex

来源 :2014天津国际干细胞论坛 | 被引量 : 0次 | 上传用户：xingyu9404
【摘 要】
：
Trithorax group proteins methylate lysine 4 of histone3 (H3K4) at active gene promoters.MLL5 protein,a member of the Trithorax protein family,has been implicated in the control of the cell cycle progr
【作 者】
：
Peipei Zhou Zhilong Wang Xiujie Yuan Cuihong Zhou Lulu Liu Xiaoling Wan Feng Zhang Xiaodan Ding Chuangui Wang Sidong Xiong Zhen Wang Jinduo Yuan Qiang Li Yan Zhang 
【机 构】
：
Key Laboratory of Molecular Virology and Immunology,Institut Pasteur of Shanghai,Chinese Academy of
【出 处】
：
2014天津国际干细胞论坛
【发表日期】
：
2014年3期
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Trithorax group proteins methylate lysine 4 of histone3 (H3K4) at active gene promoters.MLL5 protein,a member of the Trithorax protein family,has been implicated in the control of the cell cycle progression;however,the underlying molecular mechanism(s) have not been fully determined.In this study,we found that the MLL5 protein can associate with the cell cycle regulator "host cell factor" (HCF-1).
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