【摘 要】
：
背景 儿童手足口病在我国流行日益严重,2012年全国共发生手足口病2198442例,比2011年的1619706例增加35.7％,死亡569人,比2011年多死亡60例.可导致儿童手足口病的肠道病毒
【机 构】
：
东南大学医学院病原微生物与免疫学系
【出 处】
：
2013全国生物与医学纳米技术博士生学术论坛
论文部分内容阅读
背景 儿童手足口病在我国流行日益严重,2012年全国共发生手足口病2198442例,比2011年的1619706例增加35.7％,死亡569人,比2011年多死亡60例.可导致儿童手足口病的肠道病毒种类较多,其中最常见的是肠道病毒71型(EV71)和柯萨奇病毒A16型(CVA16).但近年由柯萨奇病毒A6 (CVA6)等其他肠道病毒引起的手足口病流行在国外已有多起报道.本实验室于2012年8-12月从江西九江临床诊断为手足口病患儿中采集到704份咽拭子标本(每人一份),通过RT-PCR检测,确定CVA6感染比率高达72.7％,首次确认了CVA6手足口病在我国的暴发流行.目的 通过细胞培养从患者分泌物中分离CVA6,并利用分子生物学方法鉴定,了解分离株与国内外CVA6毒株的同源性.
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