ANGIOTENSIN-(1-7) INHIBITS VASCULAR CALCIFICATION IN RATS

来源 :第二十四届长城国际心脏病学会议、亚太心脏大会暨国际心血管病预防与康复会议(The 24th Great Wall Int | 被引量 : 0次 | 上传用户：xiaoxiaoDang

【摘要】

：

Objectives Angiotensin-(1-7) [Ang-(1-7)] is a new bioactive heptapeptide in the renin-angiotensin system (RAS).It is produced mainly by the activity of angiotensin-converting enzyme 2 (ACE2) and acts

【作者】

：

Sui Yubin Yin Xinhua

【机构】

：

Department of Cardiology,The First Affiliated Hospital of Harbin Medical University,Harbin

【出处】

：

第二十四届长城国际心脏病学会议、亚太心脏大会暨国际心血管病预防与康复会议(The 24th Great Wall Int

【发表日期】

：

2013年2期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Objectives Angiotensin-(1-7) [Ang-(1-7)] is a new bioactive heptapeptide in the renin-angiotensin system (RAS).It is produced mainly by the activity of angiotensin-converting enzyme 2 (ACE2) and acts through the Mas receptor.Ang-(1-7) has potent protective effects in cardiovascular diseases, opposing many pathogenic actions of angiotensin Ⅱ (Ang Ⅱ) mediated by Ang Ⅱ type 1 (AT1) receptor.

其他文献

EFFECTS OF EXCITED β3-AR ON REVERSE CHOLESTEROL TRANSPORT IN APOLIPOPROTEIN E KNOCKOUT MICE

Objectives To study the effect of activated β3-AR on reverse cholesterol transport and arterial atherosclerotic plaques in apolipoprotein E knockout (ApoE-/-) mice.Methods Ten wide type C57BL/6J mice,

会议

MICRORNA-31 REGULATE PHENOTYPIC MODULATION OF HUMAN VASCULAR SMOOTH MUSCLE CELL VIA ITS TARGET GENE

Objectives Cellular repressor of E1A-stimulated genes (CREG) plays an important role in phenotypic modulation of VSMCs,but the mechanism of its upstream signalling regulation is not clear.Recently, mi

会议

TRANSPLANTATION OF CELLULAR REPRESSOR OF E1A-STIMULATED GENE MODIFIED EMBRYONIC STEM CELLS IMPROVES

Objectives Cellular repressor of E1A-stimulated genes (CREG) is a mannose-6-phosphate-containing secreted glycoprotein of 220 amino acids.It has been proposed that CREG acts as a ligand that enhances

会议

EFFECTS OF APELIN ON THE PHOSPHODIESTERASE 1 EXPRESSION AND OXIDATIVE STRESS LEVELS IN MOUSE KIDNEY

Objectives Apelin is a recently-discovered cardiovascular bioactive polypeptide with multiple biological effects, which is the endogenous ligand of the orphan G protein-coupled receptor-APJ receptor a

会议

ADIPONECTIN REGULATES SR Ca2+ CYCLING FOLLOWING ISCHAEMIA/REPERFUSION THROUGH SPHINGOSINE 1-PHOSPHAT

Objectives The circulating, adipocyte-secreted hormone adiponectin (APN) exerts protective effects on the heart under stress conditions.Recent study demonstrated that APN induces a marked Ca2+ influx

会议

ROSUVASTATIN PROTECTS CARDIOMYOCYTES FROM TUMOUR NECROSIS FACTOR-ALPHA INDUCED APOPTOSIS VIA MICRORN

Objectives To investigate the effects of statin, possessed pleiotropic cardioprotective effects, on cardiomyocytes apoptosis induced by TNF-α and the potential mechanisms involved.Methods Cardiomyocyt

会议

ERK5 MEDIATES ADVANCED GLYCATION END PRODUCTS-INDUCED IMPAIRMENT OF ANGIOGENIC CAPACITY IN CARDIAC E

Objectives Diabetes-induced impairment of collateral formation in ischaemic myocardium has been demonstrated both in experimental and clinical studies, which may contribute to unfavorableprognosis amo

会议

RELATIONSHIP BETWEEN PARAOXONASE 1 (PON1) GENE POLYMORPHISMS, HAPLOTYPES,CONCENTRATION, ACTIVITY AND

Objectives Paraoxonase 1 (PON1) is an high-density lipoprotein (HDL)-associated enzyme capable of inhibiting the progression of atherosclerosis, thus preventing the development of coronary artery dise

会议

CURCUMIN INHIBITS LPS-INDUCED INFLAMMATION IN RAT VASCULAR SMOOTH MUSCLE CELLS IN VITRO VIA ROS-RELA

Objectives To investigate whether curcumin (Cur) suppressed lipopolysaccharide (LPS)-induced inflammation in vascular smooth muscle cells (VSMCs) of rats, and to determine its molecular mechanisms.Met

会议

ROLE OF INTRACELLULAR CALCIUM HANDLING IN NEIGHBORING MYOCYTES IN REGULATING ADULT MYOCYTE DEDIFFERE

Objectives Adult myocyte dedifferentiation/re-differentiation (AMDR) occurs during both acute and chronic cardiac diseases.AMDR-based regenerative circuits have been considered as conduits through whi

会议

ANGIOTENSIN-(1-7) INHIBITS VASCULAR CALCIFICATION IN RATS

与本文相关的学术论文