【摘 要】
:
Histone deacetylases (HDACs) are a family of enzymes that catalyze the deacetylation of lysine side chains in chromatin, and thereby these enzymes are involved in a wide range of biological processes
【机 构】
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Laboratory of Regenerative Biology, Guangzhou Institute of Biomedicine and Health, Chinese Academy o
【出 处】
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中国化学会第十届全国天然有机化学学术会议
论文部分内容阅读
Histone deacetylases (HDACs) are a family of enzymes that catalyze the deacetylation of lysine side chains in chromatin, and thereby these enzymes are involved in a wide range of biological processes such as cell differentiation, proliferation, angiogenesis, and apoptosis1,2 Many researchers have reported that class Ⅰ HDACs were elevated expressed in many types of cancers,including gastric cancer, pancreatic cancer, colorectal cancer, prostate cancer and hepatocellular carcinoma.
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