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  5. Multifunctional DNA-Gold Nanorods as a chemo-and thermo-dual therapy for cancer treatment

Multifunctional DNA-Gold Nanorods as a chemo-and thermo-dual therapy for cancer treatment

来源 :2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会 | 被引量 : 0次 | 上传用户：qingdao2046
【摘 要】
：
Gold Nanorods (GNRs) has been explored for drug delivery due to its thermal anti-cancer function, easy preparation and modification, good biocompatibility and stability, and active accumulation and in
【作 者】
：
Nan Zhang Shasha Li Dan Liu Lili Song Haiying Hua Yongxing Zhao 
【机 构】
：
Department of Pharmaceutics, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, HeN
【出 处】
：
2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会
【发表日期】
：
2015年9期
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Gold Nanorods (GNRs) has been explored for drug delivery due to its thermal anti-cancer function, easy preparation and modification, good biocompatibility and stability, and active accumulation and intracellular delivery to tumor.Doxorubicin (DOX) has been the standard chemotherapy for cancer.To enhance the anti-cancer efficacy, chemotherapy and thermotherapy were combined in the present study.To load sufficient DOX, DOX was firstly intercalated into DNA double strands and DOX-loaded DNA was absorbed to GNRs.
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