靶向多胺代谢系统的新型药物筛选

来源 :中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议 | 被引量 : 0次 | 上传用户:helly986
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  基于蛋白质结构的计算机辅助药物筛选与设计是一个重要的研究领域,其在过去数十年取得了飞速的发展。一直以来,研究人员普遍认为能够与靶标蛋白质形成共价结合的共价药物分子会有巨大的副作用,因此共价药物的计算机辅助筛选与设计没有取得相应的发展。
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