The phenanthridine family is widely found in medicinal chemistry and material science because of the biological activity and the presence in a variety of significant natural products[1].However,there are few reports about diphenanthridine dyes.In our work,a series of 4,10-substituted diphenanthridine dyes were effectively synthesized by synthetic strategy of Pictet-Spengler reaction with 2,5-di(thiophen-2-yl)benzene-1,4-diamine and arylaldehydes(Fig.1).We have accomplished the synthesis of the 2,5-di(thiophen-2-yl)benzene-1,4-diamine in four steps[2].