Spirooxindoles are attractive heterocyclic skeletons with broad and promising activities in various therapeutic fields.[1] As this frameworks have existed in a variety of natural products and pharmace
Spirooxindoles derivatives are one of the most common skeletons found in natural products.[1] The synthesis of this kind of compounds has been long-standing challenge in organic chemistry,and consider
Hydrogen sulfide(H2S),although historically known as a toxic gas,has been recently classified as a critical cell signaling molecule,like nitric oxide(NO)and carbon monoxide(CO).
Nucleoside and their derivatives have been comprehensively applied in biology and medicine duo to their particular activities.5-Aza-2-deoxycytidine a kind of 2-deoxidization cytidine analogues,which h
Amyloid-β oligomers(AβOs)are the most important toxic species in the brains of Alzheimers disease(AD)patients.Thus,AβOs are regarded as reliable molecular biomarkers for AD diagnosis and crucial targe
Organophosphorus pesticides(OPPs)are the used for fighting the enormous number of crop-eating insects in agriculture.The majority of OPPs and their residues have high acute toxicity when absorbed by h
Sulfonamides are a kind of antibiotics for prophylaxis of dysentery and pneumonia in domestic animals,and the use of these antibiotics is defined,in order to prevent drug-resistant bacteria from being
We reported a general way to design electrochemical biosensor with a dual-function peptide probe as the receptor of target and the inducer of gold nanoparticles(AuNPs)assembly on electrode surface.To