Enhanced therapeutic effect for murine colon carcinoma through Colon 26/Ag85A-CD226 tumor cell vacci

来源 :中国免疫学会第九届全国免疫学学术大会 | 被引量 : 0次 | 上传用户:da330136324
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Objective: To examine the effects of Colon 26/Ag85A-CD226 tumor cell vaccine on colon carcinoma in mice.Methods: The recombinant pcDNA3.1-Ag85A-CD226 was constructed and stable transfected into the Colon 26 cells.The BALB/c mice were subcutaneously inoculated with Colon 26 cells and after three days, mice were immunized three times with Colon 26 cells, Colon 26/pcDNA3.1 cells, Colon 26/CD226 cells, Colon 26/Ag85A cells, or Colon 26/Ag85A-CD226 cells, which were inactivated by mitomycin C, at weekly intervals, respectively.
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