Ubiquitin-specific protease 4 (USP4) positively regulates RIG-I signaling through deubiquitination a

来源 :中国细胞生物学学会2013年全国学术大会 | 被引量 : 0次 | 上传用户：zlp_dream

【摘要】

：

Retinoic acid-inducible gene I (RIG-I) is a major cytosolic RNA sensor to detect RNA virus and initiate the antiviral innate immune response.Protein ubiquitinat

【作者】

：

Lijuan Wang Wei Zhao Chengjiang Gao

【机构】

：

DepartmentofImmunology,ShandongUniversitytheSchoolofMedicine,Jinan,Shandong,China

【出处】

：

中国细胞生物学学会2013年全国学术大会

【发表日期】

：

2013年4期

【关键词】

：

antiviral innate immunity RIG-I USP4 deubiquitination

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Retinoic acid-inducible gene I (RIG-I) is a major cytosolic RNA sensor to detect RNA virus and initiate the antiviral innate immune response.Protein ubiquitination has been shown to play an essential role in the regulation of RIG-I activation.

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Ubiquitin-specific protease 4 (USP4) positively regulates RIG-I signaling through deubiquitination a

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