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Purpose This study was to compare the difference of endometrial and subendometrial perfusion between healthy fertility and idiopathic infertility by the method of contrast-enhanced ultrasound (CEUS) with time-intensity curve (TIC) analysis.Methods This was a prospective clinical study.27 idiopathic infertile women and 21healthy fertile women took part in this study.All of them accepted CEUS on late-proliferative phase,periovulatory phase and implantation window.