Osteoprotegerin(OPG)is known to inhibit differentiation and activation of osteoclasts(Ocs)by functioning as a decoy receptor blocking interactions between RANK and RANKL.
The objectives of this study were to identify genetic polymorphisms of duck VLDLR gene,and to analyze association between combined haplotypes and abdominal fat trait in Gaoyou domestic duck.
Background: H5N1 highly pathogenic avian influenza(HPAI)has raised global concern for causing huge economic losses in poultry industry,and an effective vaccine against HPAI is highly desirable.
mTOR activation is known to suppress autophagy by phosphorylating ULK1 at S757 and deactivating its enzymatic activity.Here we report that feedback activation of the mTOR-PI3K pathway by two S6K1 inhi
Ochratoxin A(OTA),a worldwide mycotoxin found in food and feeds,is a potent nephrotoxin in animals and humans.Porcine circovirus-associated disease(PCVAD),including porcine dermatitis and nephropathy
Leflunomide is an immunosuppressive drug prescribed for treating rheumatoid arthritis(RA).Our recent study showed that A77 1726,the active metabolite of leflunomide,inhibits the activity of p70 S6 kin
[Background] A virulent pseudorabies virus(PRV)variant emerged in many porcine farms in China from 2011.Even though vaccines made of PRV Bartha K61 strain could provide protection,but poor protection
[Objective] This study aimed to investigate the potential of virus-like particles(VLPs)from rabbit hemorrhagic disease virus(RHDV)as a delivery system for foreign epitopes.