【摘 要】
：
OBJECTIVE: To observe the effects of Abnormal Savda Munziq (ASMq) on the behavior and oxidative stress response of Parkinsons disease (PD) rat models.METHODS: PD rats were produced by stereotactic inj
【机 构】
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Senior Cadre Ward, the First Affiliated Tumor Hospital of Xinjiang Medical University,Urumqi, China
【出 处】
：
2015中国老年医学和老年健康产业大会
论文部分内容阅读
OBJECTIVE: To observe the effects of Abnormal Savda Munziq (ASMq) on the behavior and oxidative stress response of Parkinsons disease (PD) rat models.METHODS: PD rats were produced by stereotactic injection of 6-OHDA into the substantia nigra compacta (SNc) and the midbrain ventral tegmental area (VTA) of the right side of the brain.We set up regular blank control group and the PD models were randomly divided into the model blank control group, the madopar group (madopar 125 mg/kg), and the low, middle and high dose of ASMq group (1 g/kg, 3 g/kg, 6 g/kg), and each group had 10 rats.The behavior of each group rats was observed before and after 40 days of treatment.After the treatment, each group got randomly 2 rats for the immunohistochemical detection for the quantity change of tyrosine hydroxylase (TH) expression.
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