论文部分内容阅读
XIAP通过调控SOX2维持鼻咽癌干细胞特性及其作为鼻咽癌干细胞治疗靶点的研究
【机 构】
:
中山大学肿瘤防治中心,协同创新中心,华南肿瘤学国家重点实验室 广州510060 中国江苏亚盛医药开
【出 处】
:
2016医学科学前沿暨第四届个体化治疗与抗肿瘤药物研究新趋向研讨会
【发表日期】
:
2016年10期
其他文献
Effects of Cytochrome P450 3A4 and non-genetic factors on initial Voriconazole serum trough concentr
会议
Rottlerin,isolated from a medicinal plant Mallotus phillippinensis,has been demonstrated to inhibit cellular growth and induce cytoxicity in glioblastoma cell lines through inhibition of calmodulin-de
会议
Antitumor activity of curcumin is involved in down-regulation of YAP/TAZ expression in pancreatic ca
Pancreatic cancer(PC)is one of the most aggressive human malignancies worldwide and is the fourth leading cause of cancer-related deaths.Curcumin(diferuloylmethane)is a polyphenol derived from the Cur
会议
2011 年开始,恶性肿瘤已经超过心脏病,已经成为全球第一大死亡原因.进入21世纪以来一直以来,以免疫学为基础建立起的肿瘤免疫疗法已成为继手术、化疗、放疗和靶向治疗后的一种新的有效疗法.针对免疫检查点的阻断是众多激活抗肿瘤免疫的有效策略之一.PD-L1,作为T 细胞表面PD-1 的配体高表达于多种恶性肿瘤细胞的表面,其与PD-1相互作用后可以抑制T 细胞的增殖,细胞因子的释放从而抑制机体对于肿瘤细
会议
CCL21 facilitates chemoresistance and cancer stem cell-like properties of colorectal cancer cells th
Tumor drug resistance is the main reason for the failure of tumor chemotherapy,but the underlying mechanisms are various,which is a big problem in the clinical treatment.A large number of studies have
会议
β-catenin/p300 signaling activation by CBP blockade induces cell senescence in wild-type or T315I-mu
Chronic myeloid leukemia(CML)is a clonal malignant disorder of pluripotent hematopoietic stem cells(HSCs)characterized by the formation of the novel breakpoint cluster region-Abelson tyrosine kinase(B
会议
Activation of GPER suppresses migration and angiogenesis of triple negative breast cancer via inhibi
Triple-negative breast cancer(TNBC)are characterized by high vascularity and frequent metastasis.Here,we found that activation of G protein-coupled estrogen receptor(GPER)by its specific agonist G-1 c
会议
Bisphenol S inactivates Hippo signaling via GPER and promotes the metastasis in triple negative brea
Background: Bisphenol A(BPA)is a chemical with widespread human exposure suspected of causing low-dose effects.Bisphenol-S(BPS)which structurally similar to BPA is intended to replace BPA in plastic.