β-catenin/p300 signaling activation by CBP blockade induces cell senescence in wild-type or T315I-mu

来源 :2016医学科学前沿暨第四届个体化治疗与抗肿瘤药物研究新趋向研讨会 | 被引量 : 0次 | 上传用户：lantaiwin

【摘要】

：

Chronic myeloid leukemia(CML)is a clonal malignant disorder of pluripotent hematopoietic stem cells(HSCs)characterized by the formation of the novel breakpoint cluster region-Abelson tyrosine kinase(B

【作者】

：

Ke Yang Li-Yan Huang Fang Wang Xiao-Kun Wang Likun Chen Xiaodong Su Xingping WU Qian-Qian Han Zhen Chen Zhi Shi Kenneth Kin Wah To Brian J.Druker Zhe-Sheng Chen Li-Wu Fu

【机构】

：

Sun Yat-sen University Cancer center,State Key Laboratory of Oncology in Southern China,Collaborativ

【出处】

：

2016医学科学前沿暨第四届个体化治疗与抗肿瘤药物研究新趋向研讨会

【发表日期】

：

2016年10期

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β-catenin/p300 signaling activation by CBP blockade induces cell senescence in wild-type or T315I-mu

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