Autophagy is a multi-step process that involves the degradation and digestion of intracellular components by the lysosome.It has been proved that many core autophagy-related molecules participate in this event.However, new component proteins that regulate autophagy are still being discovered.At present, we report PHF23 (plant homeodomain finger protein 23) with a PHD-like zinc finger domain that can negatively regulate autophagy.