The importance of the last strand at the C-terminus in βB2-crystallin stability and assembly

来源 :2013年第四届全国“跨学科蛋白质研究”学术讨论会 | 被引量 : 0次 | 上传用户:naonao7949
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  Congenital cataract is the leading cause of childhood blindness worldwide.Investigations of the effects of inherited mutations on protein structure and function not only help us to understand the molecular mechanisms underlying congenital hereditary cataract, but also facilitate the study of complicated cataract and non-lens abnormities caused by lens-specific genes.
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