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Objectives:The purpose of this clinical study was to evaluate the effectiveness of two kinds of Lion dentifrices(a dentifrice with 0.05%isopropyl methylphenol(IPMP)/0.05%dipotassium glycyrrhizinate(GK2)/0.05%tranexamic acid(TXA)and a dentifrice with 0.05%tranexamic acid only)on control of dental plaque and gingivitis,compared with placebo control dentifrice.