Modulation of the cellular distribution of human cytomegalovirus helicase by cellular factor Snapin

来源 :第十届全国病毒学学术研讨会 | 被引量 : 0次 | 上传用户：jk224wang1

【摘要】

：

　　Controlled regulation of genomic DNA synthesis is a universally conserved process for all herpesviruses including human cytomegalovirus (HCMV) and plays a k

【作者】

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Junn Luo Jun Chen Ed Yang Ao Shen Hao Gong Zenglin Pei Gengfu Xiao Songya Lu Fenyong Liu

【机构】

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StateKeyLaboratoryofVirology,CollegeofLifeSciences,WuhanUniversity,Wuhan,Hubei430072,ChinaDivisionof

【出处】

：

第十届全国病毒学学术研讨会

【发表日期】

：

2013年9期

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　　Controlled regulation of genomic DNA synthesis is a universally conserved process for all herpesviruses including human cytomegalovirus (HCMV) and plays a key role in viral pathogenesis such as persistent infections.HCMV UL105 is believed to encode the belicase of the DNA replication machinery that needs to localize in the nuclei, the site of viral DNA synthesis.

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Modulation of the cellular distribution of human cytomegalovirus helicase by cellular factor Snapin

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