Non-invasively detecting isocitrate dehydrogenase1(IDH1)mutation using water diffusion heterogeneity

来源 :中国中西医结合学会医学影像专业委员会第十五次全国学术大会暨上海市中西医结合学会医学影像专业委员会2017年学术年会 | 被引量 : 0次 | 上传用户:goodcareer
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Objective:To explore the feasibility of non-invasively detecting the status of IDH1 mutation(isocitrate dehydrogenase 1) using non-Gaussian-derived diffusion MR imaging in brain gliomas.Methods:Fifty-three cases with pathologically confirmed lowgrade glioma(WHO grade Ⅱ) were enrolled in this prospective study,who performed MR scans with the imaging protocol of TIWI,T2WI,T2-Flair,DWI(0,1000 s/mm2),eDWI(22 b-value DWI of 0-5000 s/mm2) and enhanced-T1WI.
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