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目的了解急性下呼吸道感染住院患儿中呼吸道合胞病毒(RSV)检出、流行情况及其与室外空气污染物浓度相关性。方法收集2014年4月-2015年3月河北省儿童医院因急性下呼吸道感染(ALRTI)住院5 465例患儿中鼻咽分泌物病毒检测呼吸道合胞病毒检测阳性病例,分析RSV检出及流行情况。并实时记录河北省石家庄市空气质量检测数据,进一步探讨RSV与空气污染物浓度的相关性。结果呼吸道合胞病毒检测阳性1 517例,检出率为27.76%。调查期间石家庄市空气质量(AQI)指数、PM2.5、PM10的平均值均处于较高水平。住院例数、RSV检出情况与PM2.5、NO2、SO2呈正相关,根据回归方程住院例数与SO2关系密切,呼吸道合胞病毒检出情况与PM2.5浓度关系最为密切。结论空气污染物浓度升高可增加儿童下呼吸道感染及呼吸道合胞病毒感染的几率。
Objective To investigate the prevalence and prevalence of respiratory syncytial virus (RSV) in hospitalized children with acute lower respiratory tract infection and its relationship with the concentration of outdoor air pollutants. Methods A total of 5 465 children with acute lower respiratory tract infection (ALRTI) hospitalized in Children’s Hospital of Hebei Province from April 2014 to March 2015 were enrolled in the detection of positive cases of respiratory syncytial virus in nasopharyngeal secretions, and the detection and prevalence of RSV Happening. And real-time record Shijiazhuang City, Hebei Province, air quality testing data to further explore the correlation between RSV and air pollutant concentrations. Results A total of 1 517 cases of respiratory syncytial virus were detected, the detection rate was 27.76%. Shijiazhuang City, air quality during the survey (AQI) index, PM2.5, PM10 average at a high level. There was a positive correlation between the number of hospitalizations and the detection of RSV with PM2.5, NO2 and SO2. The number of hospitalizations was closely related to SO2 according to the regression equation. The detection of respiratory syncytial virus was most closely related to the concentration of PM2.5. Conclusion The increase of air pollutant concentration may increase the risk of lower respiratory tract infection and respiratory syncytial virus infection in children.