【摘 要】
：
To explore the relationship between 5-HTergic terminals and the vestibulo-parabrachial projection neurons expressing 5-HT1A receptor (5-HT1AR) in the vestibular nuclear complex (VNC) of the rat.Tetram
【机 构】
：
Department of Anatomy and K.K.Leung Brain Research Centre, Fourth Military Medical University, Xi'a
【出 处】
：
中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the
论文部分内容阅读
To explore the relationship between 5-HTergic terminals and the vestibulo-parabrachial projection neurons expressing 5-HT1A receptor (5-HT1AR) in the vestibular nuclear complex (VNC) of the rat.Tetramethylrhodamine (TMR,for light microscopic study) and WGA-HRP (for electron microscopic study) retrograde-tract tracing techniques combined with doublelabeling immunofluorescence histochemistry and immuno-electron microscope were used to observe the relationship between 5-hydroxytryptamine (5-HT)-like immunoreactive terminals and the vestibulo-parabrachial projection neurons which may express 5-HT1AR in the rat VNC by using fluorescence microscope,confocal laser-scanning microscope and electron microscope.Following TMR injection into the parabrachial nucleus,many TMR retrogradely-labeled neurons were observed bilaterally within VNC,but with an ipsilateral predominance.Immunofluorescence histochemical staining showed that many neurons expressed 5-HT1AR-like immunoreactivity (-IR) and a few of TMR-labeled neurons showed 5-HT1AR-IR in the medial,inferior,superior,lateral vestibular nucleus (MVe,SpVe,SuVe,LVe),X nucleus and Y nucleus.
其他文献
Serotonin (5-HT) deficiency is associated with cognitive deficits and psychiatric disorders,particularly anxiety and depression,but recent evidence for the role of 5-HT is contradictory.To examine the
The lateral nucleus of the amygdala (LA) receives axonal projections from the auditory thalamus and mediates auditory fear conditioning.Tetanic electrical stimulation of the auditory thalamus induces
beta-Adrenoceptors (ARs) in the basolateral nucleus of amygdala (BLA) play an essential role in regulating synaptic plasticity and fear memory.However,little is known about the cellular and subcellula
Homeostatic regulation of synaptic properties in response to chronic alteration of neuronal activity is essential for neural circuit function,but the underlying mechanism is largely unknown.Here we fo
Substance P (SP),the first identified neuropeptide,has long been indicated to be involved in the vagal control of heart rate and cardiac functions.However,the mechanism by which SP modulate cardiac va
Little is known about how gap junctions are involved in the respiratory-related,or any other types of,physiological neuronal activity since ongoing gap junction currents have never been characterized
In the primary visual cortex,activity of neurons evoked by stimuli within the classical receptive field (CRF) can be modulated by stimuli in the extra-receptive field (ERF).This modulating effect can
The spinal cord dorsal horn is the key site for transmission and modulation of nociceptive information via synaptic connections between primary nociceptive afferent C-fibers and secondary order sensor
Objective The immature and light-insensitive retina spontaneously generates a pattern of rhythmic bursting activity.Spatially,the activity is seen to spread across the retina in the form of waves and
Activity-dependent CREB-target gene transcription is implicated in cortical dendritic development.However,the molecular mechanisms regulating CREB-target gene transcription and dendritic morphogenesis