【摘 要】
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Backgrounds:The most important pathological event in retinal degenerative diseases is the loss of retinal retinal ganglion cells (RGCs).Lots of studies demonstrate the dental pulp stem cells (DPSCs) a
【出 处】
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第六届全国眼科学研究生学术论坛暨眼科细胞及再生生物学世界大会
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Backgrounds:The most important pathological event in retinal degenerative diseases is the loss of retinal retinal ganglion cells (RGCs).Lots of studies demonstrate the dental pulp stem cells (DPSCs) as self-renewing stem cells,which can differentiate into neuronal lineages as well as RGCs in the retina,and express retinal neuronal markers just like glial fibrillary acidic protein (GFAP),polysialic acid-neural cell adhesion molecule (PSA-NCAM),rhodopsin in different period.In animal models,the fate of the surviving cells were influenced by DPSCs transplanted into the brain differentiate into functional neurons or astrocytes.
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