【摘 要】
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目的 GVHD iis the major complication after allogeneic BMT.VPA has been described as a HDAC inhibitor which had anti-inflammatory effects and could reduce the production of pro-inflammatory cytokines in
【机 构】
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上海交通大学医学院附属瑞金医院血液科 200025
【出 处】
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中华医学会血液学分会第九次全国造血干细胞移植学术会议
论文部分内容阅读
目的 GVHD iis the major complication after allogeneic BMT.VPA has been described as a HDAC inhibitor which had anti-inflammatory effects and could reduce the production of pro-inflammatory cytokines in experimental autoimmune disease models.方法 Using well characterized mouse models of MHC-mismatched transplantation, we studied the effects of VPA on GVHD severity, GVL activity and the potential mechanism.
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