RNA structureshigh throughput methods

来源 :第五届中国小核酸技术与应用学术会议 | 被引量 : 0次 | 上传用户:yuxk781224
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The most remarkable findings in the past two decades in biology include how the mammalian genome is largely transcribed and how versatile functions RNA molecules can have.RNA structure may play a critical role in defining its function and regulation.However,due to lack of information,our knowledge on RNA structural language is very limited.In this talk,I will describe our recent effort in using new chemistry and deep sequencing techniques to probe RNA structures within a tube and also inside a cell,on a genome-wide scale.
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