Modulation of Oxygen-Independent Degradation of HypoxiaInducible Factor-1α in Breast Cancer by RHBDF

来源 :第五届中国小核酸技术与应用学术会议 | 被引量 : 0次 | 上传用户：zyx_xingfu

【摘要】

：

Intermittent oxygen deficiency in cancers promotes prolonged inflammation,continuous angiogenesis,and increased drug resistance.Hypoxia inducible factor-1 (HIF1

【作者】

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李鲁远

【出处】

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第五届中国小核酸技术与应用学术会议

【发表日期】

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2015年9期

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Intermittent oxygen deficiency in cancers promotes prolonged inflammation,continuous angiogenesis,and increased drug resistance.Hypoxia inducible factor-1 (HIF1) has a pivotal role in the regulation of cellular responses to oxygen deficiency.The α-subunit of HIF1 (HIF1α) is degraded in normoxia but stabilized in hypoxia.

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Modulation of Oxygen-Independent Degradation of HypoxiaInducible Factor-1α in Breast Cancer by RHBDF

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