Discovery and identification of triple-negative breast cancer(TNBC)inhibitors

来源 :2015年全国药物化学学术会议暨第五届中英药物化学学术会议 | 被引量 : 0次 | 上传用户:kenapple1368
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  Breast cancer is one of the most common malignant tumor in women,both in the developed countries and developing countries.Triple-negative breast cancer(TNBC)refers to any breast cancer that does not express the genes for estrogen receptor(ER),progesterone receptor(PR)or HER2.
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在发达国家和发展中国家,乳腺癌都是女性最常见的恶性肿瘤之一。在发展中国家,由于预期寿命增加,城市化扩大和采用西方生活方式,乳腺癌发病率正在上升。三阴乳腺癌指雌激素受体(ER)、孕激素受体(PR)及人表皮生长因子受体2(HEK2)均呈阴性的乳腺癌患者。