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蛋白酶体抑制剂是当前药物研究的热点领域之一,20S 蛋白酶体抑制剂已取得了显著进展,19S 蛋白酶体抑制剂近年来也开始受到关注.3,5-二(亚苄基)-4-哌啶酮类化合物(1)是由天然产物姜黄素衍生而来,新近研究表明其具有良好的19S 蛋白酶体抑制作用[1-3].
姜黄素硼酸类衍生物的合成及抗肿瘤活性研究
【摘 要】
：
蛋白酶体抑制剂是当前药物研究的热点领域之一,20S 蛋白酶体抑制剂已取得了显著进展,19S 蛋白酶体抑制剂近年来也开始受到关注.3,5-二(亚苄基)-4-哌啶酮类化合物(1)是由天然产物姜黄素衍生而来,新近研究表明其具有良好的19S 蛋白酶体抑制作用[1-3].
【机 构】
：
北京大学药学院,天然药物及仿生药物国家重点实验室,北京市海淀区学院路38 号 100191
【出 处】
：
2015年全国药物化学学术会议暨第五届中英药物化学学术会议
【发表日期】
：
2015年3期
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