论文部分内容阅读
CDK-dependent formation of the SMX trinuclease complex
【机 构】
:
The Francis Crick Institute,Clare Hall Laboratories,South Mimms,UK
【出 处】
:
The 16th Ataxia-Telangiectasia Workshop (ATW-2015)6th Intern
【发表日期】
:
2015年期
其他文献
DNA damage response is required for male fertility.DNA damage repair mediates recombination between homologous chromosomes in meiotic prophase, which is ess
会议
UBE2S, a Novel Substrate of AKT1, Associates with Ku70 and Regulates DNA Repair and Glioblastoma Mul
Glioblastoma multiforme (GBM) is one of the most frequent and lethal cancers.However, the molecular events and their interplay underlying carcinogenesis rem
会议
The maintenance of genome integrity is important in all cells.To conserve genome integrity, cells developed multiple molecular pathways to repair damaged DN
会议
Chemotherapeutic and radiation treatments cause a variety of genotoxic insults that lead to cell death in rapidly proliferating cancer cells.To survive geno
会议
Ataxia Telangiectasia is a rare autosomal recessive neurodegenerative disorder caused by mutation in the ATM gene.Identification of mutations is challenging
会议
Ataxia telangiectasia (AT) is a progressive degenerative disease affecting multiple systems of the body.Key manifestations of the disease include neurologic
会议
The ATM protein kinase is implicated in the DNA damage response and in sensing DNA double strand breaks.However, recent observations have involved ATM in no
会议
Ataxia-telangiectasia (A-T) is a neurodegenerative disease with autosomal recessive inheritance and, despite being monogenic, is characterized by a very ple
会议