Blocking Follistatin-like 1 attenuates pulmonary fibrosis in mice

来源 :2012全国发育生物学大会 | 被引量 : 0次 | 上传用户:yukon_hawk
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  Idiopathic pulmonary fibrosis (IPF) is an incurable fibrosing disorder that progresses relentlessly to respiratory failure.Although the mechanisms underlying the pathogenesis of lung fibrosis are not clear, TGF-β1 indubitably plays a central role in the process.Therefore, targeting TGF-β1 signaling may be a favorable strategy for patients with IPF.
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