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  5. An exploration of evolution, maturation, expression and function relationships between homologousclu

An exploration of evolution, maturation, expression and function relationships between homologousclu

来源 :第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会 | 被引量 : 0次 | 上传用户：q3324079
【摘 要】
：
　　Background: The study aims to explore the potential relationships of evolution, maturation, expression and function between homologous/clustered miRNAs.Meth
【作 者】
：
梁廷明 杨晨 李萍 郭丽 
【机 构】
：
江苏省分子医学生物技术重点实验室,生命科学学院,南京师范大学,南京,210023流行病与卫生统计学系,公共卫生学院,南京医科大学,南京,211166
【出 处】
：
第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会
【发表日期】
：
2014年10期
【关键词】
：
microRNA (miRNA) gene cluster/family evolution expression function 
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　　Background: The study aims to explore the potential relationships of evolution, maturation, expression and function between homologous/clustered miRNAs.Methods: Based on the homologous and/or clustered relationships and their important biological roles, the several related miRNAs (mir-23, mir-27 and mir-24) are typically selected to perform analysis to track miRNA or isomiR maturation process using evolutionary and expression analysis.
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